Acute Phase Response: Implication in ST-segment Elevation Myocardial Infarction
Esin Eren1, Hamit Yasar Ellidag2, Akar Yılmaz3, Özgür Aydın4, Necat Yılmaz2, *
Identifiers and Pagination:Year: 2014
First Page: 44
Last Page: 51
Publisher ID: TOBIOCJ-8-44
Article History:Received Date: 20/1/2014
Revision Received Date: 7/3/2014
Acceptance Date: 9/3/2014
Electronic publication date: 16/5/2014
Collection year: 2014
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
We aimed to investigate the relation between serum inflammatory markers, 25OHvit-D3 and oxidative stress markers, namely paraoxonase1-arylesterase (PON1-ARE), total antioxidant status (TAS) and total oxidant status (TOS) in 30 male patients with ST–elevation myocardial infarction(STEMI) . There was negative correlation between tumor necrosis factor alpha and ARE; positive correlations between serum amyloid A(SAA) and oxidative stress index, SAA and TOS, 25OHvit-D3 and ARE. There was no statistically significant correlation between inflammation makers, oxidative stress markers and Gensini score. The main finding of our study was the tendency of inflammation markers, and oxidative stress markers, to change in relatively clear opposite directions in STEMI.