RESEARCH ARTICLE


Effects of Glucan and Vitamin D Supplementation on Obesity and Lipid Metabolism in Diabetic Retinopathy



Martina Závorková1, Vaclav Vetvicka2, *, Josef Richter3, Vlastimil Kral3, Ivana Liehnova1, Dobiasova L. Rajnohova3
1 Official Clinic of UJEP Masaryk Hospital, Regional Health, Usti and Labem, Czech Republic
2 University of Louisville, Department of Pathology, Louisville, KY, USA
3 Health Institute with headquarters in Usti and Labem, Usti and Labem, Czech Republic


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© 2018 Závorková et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Pathology, University of Louisville, Vaclav Vetvicka, 511 S. Floyd, Louisville, KY 40202, USA; Tel: 5028521612; E-mail: vaclav.vetickalouisville.edu


Abstract

Background:

Diabetes mellitus is a chronic disease manifested by an increase of blood glucose.

Objective:

To evaluate the effects of glucan and vitamin D supplementation in patients with diabetic retinopathy.

Method:

We evaluated the effects of 3-month supplementation with glucan and vitamin D in 54 patients with diabetic retinopathy. We measured levels of vitamin D, cholesterol, HDL cholesterol, and triglycerides.

Results:

The supplementation strongly decreased the cholesterol levels and improved the levels of HDL cholesterol. In addition, vitamin D levels were strongly improved, but still not at optimal values.

Conclusion:

From our data, we concluded that glucan and vitamin D supplementation strongly influence lipid metabolism and have positive effects on human health.

Keywords: Glucan, Vitamin D, Diabetes, Obesity, Diabetic retinopathy, Supplementation, Clinical trials.