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Subunit Mobility and the Chaperone Activity of Recombinant αB-Crystallin
A Krushelnitsky, *
, 1
N Mukhametshina1
Y Gogolev1
N Tarasova1
D Faizullin1
T Zinkevich2
O Gnezdilov2
V Fedotov1
Authors Info & Affiliations
, 1
N Mukhametshina1
Y Gogolev1
N Tarasova1
D Faizullin1
T Zinkevich2
O Gnezdilov2
V Fedotov1
Authors Info & Affiliations
Abstract
The comparison of the chaperone-like activity of native and covalently cross-linked human αB-crystallins has confirmed the important role of the subunit mobility in the chaperoning mechanism. Our data clearly demonstrate that the chaperone-like activity of α-crystallin is not only a surface phenomenon as was suggested by some researchers.
